NIH R25 mentored research training

R25 Structural Biology Training Program

A mentored research training program run by Dr. Davis and colleagues, pairing coursework in structural methods with hands-on bench and computational experience across the lab's active cryo-EM and cryo-ET projects.

Cohort-based, mentored research appointments
Rolling applications
Open to trainees at all levels
NIH R25

Program Goals & Eligibility

Structured, mentored training that turns capable trainees into independent structural biologists.

Program goals

  • Build a diverse pipeline of trainees equipped to run independent structural biology research programs.
  • Pair didactic coursework in structural methods with hands-on bench and computational rotations across the lab's active projects.
  • Give every trainee ownership of an independent research project, mentored one-on-one through to a publishable or presentable result.
  • Connect trainees to the broader structural biology community through workshops, conferences, and collaborating labs.

Eligibility

  • Undergraduate, graduate, postbaccalaureate, or early postdoctoral trainees.
  • Interest in structural biology, biophysics, or precision health research.
  • Priority given to candidates from backgrounds underrepresented in biomedical research, per NIH R25 program goals.
  • No prior cryo-EM or structural biology experience required.

Program Structure

A two-phase design carrying trainees from coursework to an independent, mentored research project.

Phase 01 — Foundations

Coursework & Rotations

  • 01

    Structural Methods Coursework

    Didactic training in protein biochemistry, cryo-EM/cryo-ET theory, and computational structural biology.

  • 02

    Lab Rotations

    Short rotations across the lab's active workflows — protein purification, grid preparation, data processing, and model building.

  • 03

    Responsible Conduct of Research

    Data management, reproducibility, and research ethics training, as required for NIH-funded trainees.

Phase 02 — Mentored Research

Independent Project

  • 04

    Individual Development Plan

    Trainee and mentor set project scope, milestones, and career goals at the start of the appointment.

  • 05

    One-on-One Mentorship

    Paired with a faculty or senior scientist mentor for the duration of the project, with regular progress check-ins.

  • 06

    Presentation & Dissemination

    Trainees present findings at a capstone symposium and are supported toward conference presentation or co-authorship.

Program at a Glance

Key facts for prospective applicants.

Duration

Multi-year

Coursework plus mentored research

Location

Nashville, TN

On-site, lab and microscope access

Cohort size

Small cohort

Small cohort, one-on-one mentorship

Funding

NIH R25 stipend

See application for details

What's included

Trainee stipend
Structural methods coursework
Dedicated faculty mentor
Compute & microscope access
Conference/travel support

Program Goals in Practice

What the program is designed to deliver for every trainee cohort.

Mentored trainees

Cohort-based

Since program launch

Advancement

Grad/postdoc track

Trainees mentored toward advanced positions

Publications

Trainee co-authorship

Peer-reviewed, trainee-contributed

Field retention

Long-term mentorship

Support continues beyond the appointment

Program Leadership

Directed by Dr. Davis and mentoring faculty across the lab's collaborating groups.

Dr. Jamaine Davis

Program Director — Principal Investigator, Davis Lab; structural biology & precision health.

Program Co-Director

Faculty Mentor

Application

Apply to the program

Applications are reviewed on a rolling basis by the program director and mentoring faculty. Complete the form below to submit your materials—review and admission decisions are handled there.

Ready to apply?

Email jamaine@structured-health.org with your CV and a short note about your interests.

Frequently Asked Questions

Common questions about the R25 program. [answers — placeholder]

Who is eligible to apply?

Undergraduate, graduate, postbaccalaureate, and early postdoctoral trainees with an interest in structural biology or precision health research.

Is the program funded?

Yes—trainees receive a stipend through the NIH R25 award for the duration of their appointment.

Do I need prior research experience?

No prior structural biology experience is required; some research exposure is helpful but not mandatory.

What happens after I apply?

Applications are reviewed on a rolling basis; shortlisted candidates are invited to an interview with the program director and prospective mentors.

Can I continue past the initial appointment?

Some trainees continue into extended research appointments or transition into the lab's broader training pipeline.

Who can I contact with questions?

Reach the program director directly—see contact details in the footer below.