NIH R25 mentored research training

R25 Structural Biology Training Program

A mentored research training program run by Dr. Davis and colleagues, pairing coursework in structural methods with hands-on bench and computational experience across the lab's active cryo-EM and cryo-ET projects.

Cohort-based, mentored research appointments
Rolling applications
Open to trainees at all levels
NIH R25

Program Goals & Eligibility

Structured, mentored training that turns capable trainees into independent structural biologists.

Program goals

  • Build a diverse pipeline of trainees equipped to run independent structural biology research programs.
  • Pair didactic coursework in structural methods with hands-on bench and computational rotations across the lab's active projects.
  • Give every trainee ownership of an independent research project, mentored one-on-one through to a publishable or presentable result.
  • Connect trainees to the broader structural biology community through workshops, conferences, and collaborating labs.

Eligibility

  • Undergraduate, graduate, postbaccalaureate, or early postdoctoral trainees.
  • Interest in structural biology, biophysics, or precision health research.
  • Priority given to candidates from backgrounds underrepresented in biomedical research, per NIH R25 program goals.
  • No prior cryo-EM or structural biology experience required.

Program Structure

A two-phase design carrying trainees from coursework to an independent, mentored research project.

Phase 01 — Foundations

Coursework & Rotations

  • 01

    Structural Methods Coursework

    Didactic training in protein biochemistry, cryo-EM/cryo-ET theory, and computational structural biology.

  • 02

    Lab Rotations

    Short rotations across the lab's active workflows — protein purification, grid preparation, data processing, and model building.

  • 03

    Responsible Conduct of Research

    Data management, reproducibility, and research ethics training, as required for NIH-funded trainees.

Phase 02 — Mentored Research

Independent Project

  • 04

    Individual Development Plan

    Trainee and mentor set project scope, milestones, and career goals at the start of the appointment.

  • 05

    One-on-One Mentorship

    Paired with a faculty or senior scientist mentor for the duration of the project, with regular progress check-ins.

  • 06

    Presentation & Dissemination

    Trainees present findings at a capstone symposium and are supported toward conference presentation or co-authorship.

Program at a Glance

Key facts for prospective applicants.

Duration

Multi-year

Coursework plus mentored research

Location

Nashville, TN

On-site, lab and microscope access

Cohort size

Small cohort

Small cohort, one-on-one mentorship

Funding

NIH R25 stipend

See application for details

What's included

Trainee stipend
Structural methods coursework
Dedicated faculty mentor
Compute & microscope access
Conference/travel support

Program Goals in Practice

What the program is designed to deliver for every trainee cohort.

Mentored trainees

Cohort-based

Since program launch

Advancement

Grad/postdoc track

Trainees mentored toward advanced positions

Publications

Trainee co-authorship

Peer-reviewed, trainee-contributed

Field retention

Long-term mentorship

Support continues beyond the appointment

Program Leadership

Directed by Dr. Davis and mentoring faculty across the lab's collaborating groups.

Dr. Jamaine Davis

Program Director — Principal Investigator, Davis Lab; structural biology & precision health.

Program Co-Director

Faculty Mentor

Application

Apply to the program

Applications are reviewed on a rolling basis by the program director and mentoring faculty. Complete the form below to submit your materials—review and admission decisions are handled there.

Ready to apply?

Email jamaine@structured-health.org with your CV and a short note about your interests.

Frequently Asked Questions

Common questions about the R25 program.

Who is eligible to apply?

Undergraduate, graduate, postbaccalaureate, and early postdoctoral trainees with an interest in structural biology or precision health research.

Is the program funded?

Yes—trainees receive a stipend through the NIH R25 award for the duration of their appointment.

Do I need prior research experience?

No prior structural biology experience is required; some research exposure is helpful but not mandatory.

What happens after I apply?

Applications are reviewed on a rolling basis; shortlisted candidates are invited to an interview with the program director and prospective mentors.

Can I continue past the initial appointment?

Some trainees continue into extended research appointments or transition into the lab's broader training pipeline.

Who can I contact with questions?

Reach the program director directly—see contact details in the footer below.